Fused Multiple Graphical Lasso

نویسندگان

  • Sen Yang
  • Zhisong Pan
  • Xiaotong Shen
  • Peter Wonka
  • Jieping Ye
چکیده

In this paper, we consider the problem of estimating multiple graphical models simultaneously using the fused lasso penalty, which encourages adjacent graphs to share similar structures. A motivating example is the analysis of brain networks of Alzheimer’s disease using neuroimaging data. Specifically, we may wish to estimate a brain network for the normal controls (NC), a brain network for the patients with mild cognitive impairment (MCI), and a brain network for Alzheimer’s patients (AD). We expect the two brain networks for NC and MCI to share common structures but not to be identical to each other; similarly for the two brain networks for MCI and AD. The proposed formulation can be solved using a second-order method. Our key technical contribution is to establish the necessary and sufficient condition for the graphs to be decomposable. Based on this key property, a simple screening rule is presented, which decomposes the large graphs into small subgraphs and allows an efficient estimation of multiple independent (small) subgraphs, dramatically reducing the computational cost. We perform experiments on both synthetic and real data; our results demonstrate the effectiveness and efficiency of the proposed approach.

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Testing for Differences in Gaussian Graphical Models: Applications to Brain Connectivity

Functional brain networks are well described and estimated from data with Gaussian Graphical Models (GGMs), e.g. using sparse inverse covariance estimators. Comparing functional connectivity of subjects in two populations calls for comparing these estimated GGMs. Our goal is to identify differences in GGMs known to have similar structure. We characterize the uncertainty of differences with conf...

متن کامل

On the Complexity of the Weighted Fussed Lasso

The solution path of the 1D fused lasso for an ndimensional input is piecewise linear with O(n) segments [1], [2]. However, existing proofs of this bound do not hold for the weighted fused lasso. At the same time, results for the generalized lasso, of which the weighted fused lasso is a special case, allow Ω(3) segments [3]. In this paper, we prove that the number of segments in the solution pa...

متن کامل

The group fused Lasso for multiple change-point detection

We present the group fused Lasso for detection of multiple change-points shared by a set of cooccurring one-dimensional signals. Change-points are detected by approximating the original signals with a constraint on the multidimensional total variation, leading to piecewise-constant approximations. Fast algorithms are proposed to solve the resulting optimization problems, either exactly or appro...

متن کامل

Exact Hybrid Covariance Thresholding for Joint Graphical Lasso

This paper studies precision matrix estimation for multiple related Gaussian graphical models from a dataset consisting of different classes, based upon the formulation of this problem as group graphical lasso. In particular, this paper proposes a novel hybrid covariance thresholding algorithm that can effectively identify zero entries in the precision matrices and split a large joint graphical...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

عنوان ژورنال:
  • SIAM Journal on Optimization

دوره 25  شماره 

صفحات  -

تاریخ انتشار 2015